Diazepam pregnancy






Panic attacks but scared to take diazepam - Netmums

10/24/2014
12:40 | Author: Lauren Wood

Diazepam pregnancy
Panic attacks but scared to take diazepam - Netmums

I'm 17 weeks pregnant an have started havin panic attacks. Doctor has given me 2mg diazepam tablets to take when i get an attack My dr took me off all mediacation when i got pregnant including anti d's and diazepan said.

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Use of phenytoin, phenobarbital, or diazepam during pregnancy and

12/23/2014
10:20 | Author: Lauren Wood

Diazepam pregnancy
Use of phenytoin, phenobarbital, or diazepam during pregnancy and

Use of phenytoin, phenobarbital, or diazepam during pregnancy and risk of congenital abnormalities: a case-time-control study. Kjaer D, Horvath-Puhó E.

National Center for Biotechnology Information, U.S. National Library of Medicine 8600 Rockville Pike, Bethesda MD, 20894 USA.

Case-control studies are often used to examine putative teratogenic drug effects during organogenesis but these studies are subject to confounding by indication, recall, and participation bias. The case-time-control approach is less susceptible to these sources of bias. We studied congenital abnormalities following exposure to phenytoin, phenobarbital, and diazepam in early pregnancy, i.e., second and third month, compared to mid-pregnancy, i.e., fifth and sixth month of pregnancy.

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We analyzed data from the Hungarian Case-Control Surveillance of Congenital Abnormalities in a case-time-control study.

The study included 22 843 children with congenital abnormalities (cases) and 38 151 children with no abnormalities (controls). Overall, odds ratio (OR) for congenital abnormalities after exposure to one of the three drugs in early pregnancy was 1.2 (95% confidence interval (CI): 1.0-1.4). Among children exposed to phenytoin OR for congenital abnormalities was 3.7 (95%CI: 0.3-49.6), for children exposed to phenobarbital the OR was 1.1 (95%CI 0.7-1.7), and for diazepam, OR for congenital abnormalities was 1.2 (95%CI: 1.0-1.4).

The associations we found between the drugs examined and congenital abnormalities were either only borderline significant or not statistically significant. The case-time-control study provides an interesting way of using existing case-control data to study rare side effect of drugs taken during pregnancy.

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The effects of benzodiazepine use during pregnancy and lactation

10/22/2014
08:20 | Author: Lauren Wood

Diazepam pregnancy
The effects of benzodiazepine use during pregnancy and lactation

Diazepam and chlordiazepoxide are amongst the drugs most frequently or diabetes all of which have an intrinsic risk in pregnancy, and some were on.

National Center for Biotechnology Information, U.S. National Library of Medicine 8600 Rockville Pike, Bethesda MD, 20894 USA.

Although there are a number of studies and individual case reports concerning the use of benzodiazepines in human pregnancy, the data concerning teratogenicity and effects on postnatal development and behaviour are inconsistent. There is evidence from studies in the 1970s that first trimester exposure to benzodiazepines in utero has resulted in the birth of some infants with facial clefts, cardiac malformations, and other multiple malformations, but no syndrome of defects.

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Diazepam use during pregnancy a review of the literature

8/21/2014
06:20 | Author: Lauren Wood

Diazepam pregnancy
Diazepam use during pregnancy a review of the literature

Del Med J. 2002 Mar;74(3):127-35. Diazepam use during pregnancy: a review of the literature. Iqbal MM, Sobhan T, Aftab SR, Mahmud SZ. Antianxiety.

National Center for Biotechnology Information, U.S. National Library of Medicine 8600 Rockville Pike, Bethesda MD, 20894 USA.

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Antianxiety medications such as benzodiazepines (BZDs) are frequently and appropriay used to ameliorate the anxiety symptoms of depression, dysthymic disorder, panic disorder, agoraphobia, obsessive-compulsive disorder, generalized anxiety disorder, eating disorder, and many personality disorders. Pregnancy may be accompanied by anxiety necessitating therapeutic intervention by anxiolytic drugs like BZD. Keeping in view the potential risks of teratogenicity and direct neonatal toxicity, BZDs with established safety records should be used, while avoiding exposure in the first trimester, especially with multidrug regimens, and prescribing the lowest dose for the shortest duration. This literature review highlights information from various sources regarding safety data of exposure of pregnant and lactating mothers to long-acting BZDs, especially diazepam.

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Benzodiazepines and Pregnancy - Illinois Teratogen Information

6/20/2014
04:40 | Author: Lauren Wood

Diazepam pregnancy
Benzodiazepines and Pregnancy - Illinois Teratogen Information

Most of the information on benzodiazepine use during pregnancy is based on diazepam. Although initial studies suggested an association between first.

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The possible teratogenicity of benzodiazepines was raised again when Laegrid et al. (1989) reported eight infants with birth defects whose mothers had taken diazepam or oxazepam while pregnant. Most of the abnormalities involved either facial defects or neurological problems. This study was criticized because photographs of the affected children revealed a physical appearance similar to that seen in Zellweger syndrome, an autosomal recessive condition.

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